Adcetris 50mg infusion vial
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Adcetris by Takeda contains brentuximab vedotin, an antibody-drug conjugate that combines a CD30-targeting monoclonal antibody with a cell-killing medicine. Targeted treatment can still affect healthy tissues and cause serious side effects.
What is Adcetris used for?
Adcetris is used in selected lymphoma treatment regimens, including certain cases of Hodgkin lymphoma, systemic anaplastic large cell lymphoma and CD30-positive cutaneous T-cell lymphoma. Eligibility depends on the specific diagnosis, disease markers, prior treatment and locally approved product information.
Product details
- Brand: Adcetris.
- Manufacturer: Takeda.
- Active ingredient: brentuximab vedotin.
- Strength: 50 mg per vial.
- Form: powder for preparation of an intravenous infusion.
Preparation and treatment schedule
Reconstitution, dilution, dose selection, infusion timing and treatment cycles are managed by the oncology team using the manufacturer's instructions and the prescribed regimen. Treatment schedules vary; there is no single schedule or cycle count suitable for every patient.
Important precautions
Important risks include peripheral neuropathy, low blood cell counts, serious infections and rare serious neurological complications such as progressive multifocal leukoencephalopathy (PML). Combination with bleomycin presents a serious lung-toxicity risk and must be checked against the approved product information. Pregnancy, breastfeeding and contraception require specialist advice.
Possible side effects
Possible side effects include tingling or numbness in the hands or feet, fatigue, nausea, diarrhoea, constipation and reduced white blood cell counts. New neurological symptoms or signs of infection require prompt medical attention. Refer to the product leaflet for full safety information.
Frequently asked questions
What does Adcetris target?
Brentuximab vedotin targets CD30, a protein found on certain lymphoma cells.
How many treatment cycles are needed?
The oncology team determines the number of cycles according to the treatment regimen, response and side effects. A product listing cannot predict cure or treatment duration.
How should the vial be stored?
Follow the exact storage instructions on the supplied pack and manufacturer's leaflet. Prepared infusions have separate handling and storage requirements.