Ambisome 50mg intravenous infusion vial
Choose delivery option:
Choose from our selected products for you
Shop ProductsAmbisome 50mg powder for intravenous infusion
Ambisome 50mg by Gilead contains amphotericin B in a liposomal formulation. It is a specialist antifungal medicine used for serious systemic fungal infections. The vial contains powder requiring preparation before intravenous infusion; it is not a ready-to-infuse solution.
What is Ambisome used for?
Ambisome is used for serious fungal infections according to the specialist's diagnosis and the locally approved product information. Specialist uses can include selected systemic fungal infections, empirical treatment in patients with persistent fever and neutropenia, and visceral leishmaniasis. Suitability depends on the infection, patient history and treatment protocol.
Product details
- Brand: Ambisome.
- Manufacturer: Gilead.
- Active ingredient: liposomal amphotericin B.
- Strength: 50 mg per vial.
- Form: powder for preparation of an intravenous infusion.
- Presentation: one vial.
Why the formulation matters
Liposomal amphotericin B differs from other amphotericin B formulations. These products are not interchangeable on a milligram-for-milligram basis. The formulation does not eliminate the risk of kidney problems or infusion reactions.
Preparation and administration
Reconstitution, dilution, compatible infusion fluids and line handling must follow the manufacturer's instructions for the supplied product. Preparation and infusion are managed by the clinical team.
Important precautions
Kidney function and blood electrolyte levels, including potassium and magnesium, may require monitoring. A history of allergy to amphotericin B or any product ingredient must be considered before treatment.
Possible side effects
Possible side effects include fever, chills, infusion reactions, nausea, vomiting, diarrhoea, changes in kidney function, and low potassium or magnesium levels. Serious allergic reactions can occur. Refer to the product leaflet for complete safety information.
Frequently asked questions
Is Ambisome ready for immediate infusion?
No. The powder must be prepared and diluted according to the manufacturer's instructions.
Can another amphotericin B product replace it directly?
No. Different formulations require their own dosing and preparation instructions.
How should an unopened vial be stored?
Follow the exact storage conditions on the supplied pack and leaflet. Instructions for prepared solutions differ from those for unopened vials.
Can it be mixed with other medicines?
Do not assume compatibility. The clinical team must check the manufacturer's infusion-fluid and line-compatibility instructions.