Actemra 400mg/20 ml infusion vial
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Actemra by Roche contains tocilizumab, a biological monoclonal antibody that blocks interleukin-6 (IL-6) receptors involved in inflammatory signalling. This listing is for the 400 mg/20 ml vial.
What is Actemra used for?
Actemra is used for rheumatoid arthritis under specialist supervision. Intravenous tocilizumab also has specialist uses in certain forms of juvenile idiopathic arthritis and CAR-T-associated cytokine release syndrome, subject to local approved indications and patient eligibility. It is not a general treatment for every inflammatory condition.
Product details
- Brand: Actemra.
- Manufacturer: Roche.
- Active ingredient: tocilizumab.
- Strength: 400 mg in 20 ml.
- Form: concentrate for solution for intravenous infusion.
- Presentation: one vial.
Preparation and administration
This presentation requires preparation and dilution for intravenous infusion. Preparation, infusion rate and monitoring are determined by the clinical team using the manufacturer's instructions and prescribed treatment plan.
Important precautions
Assessment of infection risk, tuberculosis history, blood counts and liver function may be needed before and during treatment. A history of diverticulitis or other gastrointestinal problems should be discussed with the treating specialist.
Possible side effects
Possible side effects include headache, raised blood pressure, infusion or allergic reactions, infections, and changes in liver enzymes or blood cholesterol. The product leaflet provides the full safety information.
Frequently asked questions
What does this vial contain?
Each 20 ml vial contains 400 mg of tocilizumab.
Is this a pre-filled injection pen?
No. This product is a concentrate for intravenous infusion.
How should Actemra be stored?
Follow the storage instructions on the supplied pack and manufacturer's leaflet. Storage requirements after dilution differ from those for an unopened vial.
Can a diluted infusion be kept for later use?
The clinical team must follow the manufacturer's validated storage limits and aseptic preparation requirements. Do not assume that a prepared infusion remains suitable for later use.