Actemra 80mg/4 ml infusion vial
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Actemra 80mg/4 ml by Roche contains tocilizumab, a biological monoclonal antibody that blocks interleukin-6 (IL-6) receptors involved in inflammatory signalling. Each vial contains 80 mg in 4 ml, equivalent to 20 mg/ml.
What is Actemra used for?
Actemra is used for rheumatoid arthritis under specialist supervision. Intravenous tocilizumab also has specialist uses in certain forms of juvenile idiopathic arthritis and CAR-T-associated cytokine release syndrome, subject to local approved indications and patient eligibility. The 80 mg vial strength does not by itself determine a patient's dose or suitability for treatment.
Product details
- Brand: Actemra.
- Manufacturer: Roche.
- Active ingredient: tocilizumab.
- Strength: 80 mg/4 ml (20 mg/ml).
- Form: concentrate for solution for intravenous infusion.
- Presentation: one vial.
Preparation and use
This presentation requires preparation and dilution for intravenous infusion. The clinical team determines the required dose, preparation, infusion rate and monitoring using the manufacturer's instructions and prescribed treatment plan.
Important precautions
Assessment of infection risk, tuberculosis history, blood counts and liver function may be needed before and during treatment. Treatment suitability requires individual medical assessment.
Possible side effects
Possible side effects include headache, increased blood pressure, infusion or allergic reactions, infections, and changes in liver enzymes or cholesterol. Refer to the product leaflet for complete safety information.
Frequently asked questions
What does the 80 mg vial contain?
Each vial contains 80 mg of tocilizumab in 4 ml.
Is this a children's dose?
No. The vial strength is not a patient-specific dose. Treatment and dosing depend on the indication and specialist assessment.
Is this the same presentation as an injection pen?
No. This product is a concentrate for intravenous infusion.
How should the vial be stored?
Follow the storage instructions on the supplied pack and manufacturer's leaflet. Storage requirements after dilution differ from those for an unopened vial.